Seminario impartido por Nora Ventosa, del ICMAB-CSIC, y CEO-CSO de Delbios Pharmaceuticals
Molecular nanoparticles, such as nanovesicles, solid lipid nanoparticles and polymeric micelles, are promising multimolecular assemblies for the development of several type of biomedical products like therapeutics, contrast agents, analytical probes and vaccines. Many of these molecular nanoparticles are in clinical use as vaccines and drugs. Despite their versatility, a high control of particle-to-particle heterogeneity is necessary for an optimal performance of nanoparticle-based formulations. Thus, the formation stage of these supramolecular entities must be tightly controlled in order to achieve a homogeneous assembling of the different molecular components constituting the nanoparticle nanostructure. In this regard, one of the difficulties for the arrival to the clinics of nanoparticle based pharmaceutical formulations, are the difficulties in the scale-up and GMP manufacturing. In my lecture I will focus on the contribution that processes, based on the use of green compressed gasses, are doing to bring molecular nanoparticle based medicines from the lab to the clinics and I will present some nanoparticle-based formulations for therapy and diagnosis, produced in our lab, which are currently developed in the frame of interdisciplinary research projects.
Ponente del seminario: Nora Ventosa
Fecha del seminario: 22/10/2025 12:00
Lugar del seminario: Salón de actos del IQF