Seminario impartido por Beatriz Pelaz, del CIQUS
Nanotechnology enables the development of multifunctional materials through the self-assembly of composite nanostructures that integrate inorganic or organic nanoparticles (NPs) with biomolecules. These hybrid systems offer powerful tools for drug delivery, yet several challenges remain—such as understanding and controlling biomolecule–NP interactions (e.g., biomolecular corona formation), preventing premature intracellular degradation, and achieving selective targeting of specific cells or tissues. The design of effective nanomedicines requires features including immune evasion, minimized off-target accumulation (e.g., in the liver or spleen), extended circulation times, and enhanced therapeutic efficacy. Smart nanocarriers have emerged as a promising strategy to overcome these barriers. This presentation will explore cutting-edge approaches in nanocarrier engineering, focusing on systems such as biomimetic platforms, DNA origami structures, and stimuli-responsive nanocomposites that collectively enhance delivery performance. Each of these technologies contributes unique advantages: DNA origami offers nanoscale precision for molecular positioning; biomimetic carriers replicate natural cellular features to improve biological interactions; and stimuli-responsive materials (e.g., plasmonic nanoparticles) allow dynamic control over drug release. Their integration enables the creation of advanced, multifunctional colloidal systems with intelligent behavior and broad potential in targeted drug delivery and precision medicine.
Ponente del seminario: Beatriz Pelaz García
Fecha del seminario: 18/06/2025 09:30
Lugar del seminario: Salón de actos del IQF